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"The
Genome Center was always intended to be a center that would allow
for very high throughput analysis of complex genomes, including, of
course, the human genome. The improvement in our knowledge in human
genetics in the last few years has been so dramatic that we are now
in a very fortunate position. The availability of the human genome
sequence means that we can use that information and analyze diseases
and individuals that we are interested in very rapidly, much more
rapidly than has been possible in the past.
—Eli Hatchwell, physician and medical geneticist |
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"The
Genome Center in Cold Spring Harbor started about a year ago. Initially,
the genomics program focused on sequencing the DNA of
model
organisms
such as plants, humans and mice. Soon after, Cold Spring
Harbor moved into functional genomics, and there is a strong bioinformatics
group here [that uses computers to compare and analyze sequences].
There are also several other groups here, including my own, who are
using functional genomic approaches to really understand all the model
organism sequences (which we now have)—what their purpose is,
and how they’re involved in human diseases."
—Vivek Mittal, researcher in cancer genomics and DNA array technology at Cold Spring Harbor Laboratory (CHSL) |
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"The
primary goal is discovery, particularly in fundamental areas, and
there is sufficient room made available for investigators to pursue
their own interests. From that point of view, I think Cold Spring
Harbor is second to none in terms of giving its scientists the freedom
to pursue their scientific interests."
—Eli Hatchwell, physician and medical geneticist |
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In this video, medical geneticist Eli Hatchwell and cancer researcher
Vivek Mittal of the Genome Center at Cold Spring Harbor Laboratory
show the process of creating a DNA microarray. This powerful, high-tech
tool uses robotics to help scientists study the genetics of cancer
and other diseases.
(Watch QuickTime movie) ... help (Watch RealMedia movie) ... help |
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